Deep learning diagnostic and severity-stratification for interstitial lung diseases and chronic obstructive pulmonary disease in digital lung auscultations and ultrasonography: clinical protocol for an observational case-control study.

Journal: BMC pulmonary medicine
PMID:

Abstract

BACKGROUND: Interstitial lung diseases (ILD), such as idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP), and chronic obstructive pulmonary disease (COPD) are severe, progressive pulmonary disorders with a poor prognosis. Prompt and accurate diagnosis is important to enable patients to receive appropriate care at the earliest possible stage to delay disease progression and prolong survival. Artificial intelligence-assisted lung auscultation and ultrasound (LUS) could constitute an alternative to conventional, subjective, operator-related methods for the accurate and earlier diagnosis of these diseases. This protocol describes the standardised collection of digitally-acquired lung sounds and LUS images of adult outpatients with IPF, NSIP or COPD and a deep learning diagnostic and severity-stratification approach.

Authors

  • Johan N Siebert
    Division of Paediatric Emergency Medicine, Department of Women, Child and Adolescent, Geneva University Hospitals, 47 Avenue de la Roseraie, 1205, Geneva, Switzerland. Johan.Siebert@hcuge.ch.
  • Mary-Anne Hartley
    Intelligent Global Health, Machine Learning and Optimization (MLO) Laboratory, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
  • Delphine S Courvoisier
    Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Marlène Salamin
    Division of Pulmonology, Hospital of Valais, Sion, Switzerland.
  • Laura Robotham
    Division of Pulmonology, Hospital of Valais, Sion, Switzerland.
  • Jonathan Doenz
    Machine Learning and Optimization (MLO) Laboratory, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
  • Constance Barazzone-Argiroffo
    Paediatric Pulmonology Unit, Department of Women, Child and Adolescent, University Hospitals of Geneva, Geneva, Switzerland.
  • Alain Gervaix
    Department of Pediatrics, Gynecology and Obstetrics, University Hospitals of Geneva, Geneva, Switzerland.
  • Pierre-Olivier Bridevaux
    Division of Pulmonology, Hospital of Valais, Sion, Switzerland.