Deep learning in MRI-guided radiation therapy: A systematic review.

Journal: Journal of applied clinical medical physics
PMID:

Abstract

Recent advances in MRI-guided radiation therapy (MRgRT) and deep learning techniques encourage fully adaptive radiation therapy (ART), real-time MRI monitoring, and the MRI-only treatment planning workflow. Given the rapid growth and emergence of new state-of-the-art methods in these fields, we systematically review 197 studies written on or before December 31, 2022, and categorize the studies into the areas of image segmentation, image synthesis, radiomics, and real time MRI. Building from the underlying deep learning methods, we discuss their clinical importance and current challenges in facilitating small tumor segmentation, accurate x-ray attenuation information from MRI, tumor characterization and prognosis, and tumor motion tracking. In particular, we highlight the recent trends in deep learning such as the emergence of multi-modal, visual transformer, and diffusion models.

Authors

  • Zach Eidex
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Yifu Ding
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Jing Wang
    Endoscopy Center, Peking University Cancer Hospital and Institute, Beijing, China.
  • Elham Abouei
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Richard L J Qiu
    Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, United States of America.
  • Tian Liu
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
  • Tonghe Wang
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322.
  • Xiaofeng Yang
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.