Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.

Journal: Endocrine
PMID: 29274063

Abstract

PURPOSE: Growth hormone (GH) therapy in adults alters thyroid function, and acromegaly often involves thyroid disease. The present study aimed to elucidate roles and mechanisms of GH in regulating thyroid function.

Authors

  • Ichiro Yamauchi
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. ichiroy@kuhp.kyoto-u.ac.jp.
  • Yoriko Sakane
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Takafumi Yamashita
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Keisho Hirota
  • Yohei Ueda
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Yugo Kanai
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Yui Yamashita
    Department of Internal Medicine, Otsu Red Cross Hospital, 1-1-35 Nagara, Otsu, Shiga, 520-8511, Japan.
  • Eri Kondo
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, 54 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Toshihito Fujii
  • Daisuke Taura
  • Masakatsu Sone
  • Akihiro Yasoda
  • Nobuya Inagaki

Keywords

External Resources

Popular Topics
Recent Journals