AIMC Topic: Dwarfism, Pituitary

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Development and Validation of a Prediction Rule for Growth Hormone Deficiency Without Need for Pharmacological Stimulation Tests in Children With Risk Factors.

Frontiers in endocrinology Feb 3, 2021
INTRODUCTION: Practice guidelines cannot recommend establishing a diagnosis of growth hormone deficiency (GHD) without performing growth hormone stimulation tests (GHST) in children with risk factors, due to the lack of sufficient evidence.
Humans Machine Learning Algorithms Brain Female Reproducibility of Results Risk Factors Male Human Growth Hormone Cohort Studies Child, Preschool Child Predictive Value of Tests Body Height Practice Guidelines as Topic Dwarfism, Pituitary
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Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.

Endocrine Dec 22, 2017
PURPOSE: Growth hormone (GH) therapy in adults alters thyroid function, and acromegaly often involves thyroid disease. The present study aimed to elucidate roles and mechanisms of GH in regulating thyroid function.
Humans Retrospective Studies Female Young Adult Adult Male Middle Aged Thyroid Gland Human Growth Hormone Hormone Replacement Therapy Cell Line Thyroxine Triiodothyronine Gene Expression Regulation Acromegaly Dwarfism, Pituitary Iodide Peroxidase Iodothyronine Deiodinase Type II
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