AIMC Topic: Triiodothyronine

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Machine learning model for differentiating malignant from benign thyroid nodules based on the thyroid function data.

BMJ open May 7, 2025
OBJECTIVES: To develop and validate a machine learning (ML) model to differentiate malignant from benign thyroid nodules (TNs) based on the routine data and provide diagnostic assistance for medical professionals.
Middle Aged Thyroid Gland Thyroid Neoplasms Adult Male Autoantibodies Thyroxine Triiodothyronine Diagnosis, Differential Thyroid Function Tests Thyroid Nodule Humans Female Aged Machine Learning
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The Prevalence of Euthyroid Hypertriiodothyroninemia in Newly Diagnosed Multiple Myeloma and its Clinical Characteristics.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists Dec 13, 2020
OBJECTIVE: To evaluate the prevalence of euthyroid hypertriiodothyroninemia and/or hyperthyroxinemia and its clinical characteristics in multiple myeloma (MM) patients.
Triiodothyronine Thyrotropin Thyroxine Multiple Myeloma Humans Prevalence
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Artificial intelligence may offer insight into factors determining individual TSH level.

PloS one May 20, 2020
The factors that determine Serum Thyrotropin (TSH) levels have been examined through different methods, using different covariates. However, the use of machine learning methods has so far not been studied in population databases like NHANES (National...
Retrospective Studies Female Male Artificial Intelligence Machine Learning Humans Triiodothyronine Thyrotropin Body Mass Index Thyroxine Age Factors Ethnicity
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Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.

Endocrine Dec 22, 2017
PURPOSE: Growth hormone (GH) therapy in adults alters thyroid function, and acromegaly often involves thyroid disease. The present study aimed to elucidate roles and mechanisms of GH in regulating thyroid function.
Iodide Peroxidase Middle Aged Iodothyronine Deiodinase Type II Humans Acromegaly Thyroid Gland Female Dwarfism, Pituitary Human Growth Hormone Retrospective Studies Young Adult Thyroxine Adult Hormone Replacement Therapy Cell Line Male Triiodothyronine Gene Expression Regulation
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The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer.

Hormones & cancer Dec 19, 2017
Ovarian cancer is a highly metastatic disease. The metastatic potential is enhanced by epithelial to mesenchymal transition (EMT) in which αvβ3 integrin plays a role. Thyroid hormones (L-thyroxine, T4, and 3,5,3'-triiodo-L-thyronine, T3) bind this in...
Female Cell Line, Tumor Signal Transduction Ovarian Neoplasms Gene Expression Regulation, Neoplastic Humans Triiodothyronine beta Catenin Vimentin Thyroxine Cadherins Snail Family Transcription Factors Zonula Occludens-1 Protein Integrin alphaVbeta3 Thyroid Hormones Zinc Finger E-box-Binding Homeobox 1 Epithelial-Mesenchymal Transition
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Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan.

Medicine Aug 26, 2022
Graves disease (GD) and type 2 diabetes mellitus (T2DM) both impair liver function; we therefore explored the possibility of a relationship among diabetic control, thyroid function, and liver function. This retrospective, cross-sectional study compar...
Aspartate Aminotransferases Glutamates Receptor Protein-Tyrosine Kinases Triiodothyronine Alanine Transaminase Taiwan Thyrotropin Thyroxine Graves Disease Glycated Hemoglobin Retrospective Studies Cross-Sectional Studies Humans Diabetes Mellitus, Type 2 Biomarkers
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