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Acromegaly

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[Expression of plasma microRNA in patients with acromegaly].

Problemy endokrinologii
BACKGROUND: microRNA is a class of small non-coding RNA molecules involved in posttranscriptional regulation of gene expression. MicroRNAs are detectable in blood in stable concentrations, which makes them promising biomarkers for various diseases.

Development and Interpretation of Multiple Machine Learning Models for Predicting Postoperative Delayed Remission of Acromegaly Patients During Long-Term Follow-Up.

Frontiers in endocrinology
Some patients with acromegaly do not reach the remission standard in the short term after surgery but achieve remission without additional postoperative treatment during long-term follow-up; this phenomenon is defined as postoperative delayed remiss...

Identifying Facial Features and Predicting Patients of Acromegaly Using Three-Dimensional Imaging Techniques and Machine Learning.

Frontiers in endocrinology
Facial changes are common among nearly all acromegalic patients. As they develop slowly, patients often fail to notice such changes before they become obvious. Consequently, diagnosis and treatment are often delayed. So far, convenient and accurate ...

Constructing an automatic diagnosis and severity-classification model for acromegaly using facial photographs by deep learning.

Journal of hematology & oncology
Due to acromegaly's insidious onset and slow progression, its diagnosis is usually delayed, thus causing severe complications and treatment difficulty. A convenient screening method is imperative. Based on our previous work, we herein developed a new...

Machine learning in predicting early remission in patients after surgical treatment of acromegaly: a multicenter study.

Pituitary
PURPOSE: Accurate prediction of postoperative remission is beneficial for effective patient-physician communication in acromegalic patients. This study aims to train and validate machine learning prediction models for early endocrine remission of acr...

Machine Learning-based Prediction Model for Treatment of Acromegaly With First-generation Somatostatin Receptor Ligands.

The Journal of clinical endocrinology and metabolism
CONTEXT: Artificial intelligence (AI), in particular machine learning (ML), may be used to deeply analyze biomarkers of response to first-generation somatostatin receptor ligands (fg-SRLs) in the treatment of acromegaly.

Real-time detection of acromegaly from facial images with artificial intelligence.

European journal of endocrinology
OBJECTIVE: Despite improvements in diagnostic methods, acromegaly is still a late-diagnosed disease. In this study, it was aimed to automatically recognize acromegaly disease from facial images by using deep learning methods and to facilitate the det...

Evaluation of the impact Of ChatGPT support on acromegaly management and patient education.

Endocrine
PURPOSE: ChatGPT is a widely used artificial intelligence modeling tool. Healthcare is one potential area of use of ChatGPT. This study aimed to test the usability and reliability of ChatGPT in acromegaly, which is less known in society and should be...

Federated Learning for Predicting Postoperative Remission of Patients with Acromegaly: A Multicentered Study.

World neurosurgery
BACKGROUND: Decentralized federated learning (DFL) may serve as a useful framework for machine learning (ML) tasks in multicentered studies, maximizing the use of clinical data without data sharing. We aim to propose the first workflow of DFL for ML ...

Acromegaly facial changes analysis using last generation artificial intelligence methodology: the AcroFace system.

Pituitary
PURPOSE: To describe the development of the AcroFace system, an AI-based system for early detection of acromegaly, based on facial photographs analysis.