Deep learning parametric response mapping from inspiratory chest CT scans: a new approach for small airway disease screening.

Journal: Respiratory research
PMID:

Abstract

OBJECTIVES: Parametric response mapping (PRM) enables the evaluation of small airway disease (SAD) at the voxel level, but requires both inspiratory and expiratory chest CT scans. We hypothesize that deep learning PRM from inspiratory chest CT scans can effectively evaluate SAD in individuals with normal spirometry.

Authors

  • Bin Chen
    Department of Otorhinolaryngology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China.
  • Ziyi Liu
    College of Biosystems Engineering and Food Science, Zhejiang University, 866 Yuhangtang Road, 5 Hangzhou 310058, China.
  • Jinjuan Lu
    Department of Radiology, Shanghai Geriatric Medical Center, Shanghai, China.
  • Zhihao Li
    Heilongjiang University of CM, Harbin 150040, China.
  • Kaiming Kuang
    Dianei Technology, Shanghai, P.R. China.
  • Jiancheng Yang
    Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai, P.R. China.
  • Zengmao Wang
    School of Computer Science, Wuhan University, Wuhan, 430072, China; Hubei LuoJia Laboratory, Wuhan, 430072, China; Artificial Intelligence Institute of Wuhan University, Wuhan, 430072, China; National Engineering Research Center for Multimedia Software, Wuhan, 430072, China. Electronic address: wangzengmao@whu.edu.cn.
  • Yingli Sun
    Central Laboratory, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
  • Bo Du
    School of Computer Science, Wuhan University, Wuhan, 430072, China. Electronic address: remoteking@whu.edu.cn.
  • Lin Qi
    a Sino-Dutch Biomedical and Information Engineering School , Northeastern University , Shenyang , Liaoning , China.
  • Ming Li
    Radiology Department, Huadong Hospital, Affiliated with Fudan University, Shanghai, China.