Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel.

Journal: Phytochemical analysis : PCA
PMID: 29266486

Abstract

INTRODUCTION: Paclitaxel (Tax) is a diterpene alkaloid isolated from Taxus species and has proved clinically effective in treating a number of malignancies. Current quantitative analytical methods for Tax such as high-performance liquid chromatography (HPLC) often involve complicated sample preparation procedures with low recovery rates.

Authors

  • Qian Cui
    Department of Radiology, Tianjin First Center Hospital, Tianjin 300192, China. Corresponding author: Shen Wen, Email: shenwen66happy@163.com.
  • Hiroyuki Tanaka
    Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
  • Yukihiro Shoyama
    Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Japan.
  • Hao-Ting Ye
    School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
  • Fang Li
    Department of General Surgery, Chongqing General Hospital, Chongqing, China.
  • En-Wei Tian
    School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
  • Ying-Song Wu
    School of Biotechnology, Southern Medical University, Guangzhou, China.
  • Zhi Chao
    School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.

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