Integration of transcriptomics and machine learning for insights into breast cancer: exploring lipid metabolism and immune interactions.

Journal: Frontiers in immunology
Published Date: Oct 25, 2024

Abstract

BACKGROUND: Breast cancer (BRCA) represents a substantial global health challenge marked by inadequate early detection rates. The complex interplay between the tumor immune microenvironment and fatty acid metabolism in BRCA requires further investigation to elucidate the specific role of lipid metabolism in this disease.

Authors

  • Xiaohan Chen
    School of Software Engineering, Tongji University, Shanghai, China.
  • Jinfeng Yi
    Department of Basic Medical Sciences, Harbin Medical University, Harbin, China.
  • Lili Xie
    Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, China.
  • Tong Liu
    Intensive Care Medical Center, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, People's Republic of China.
  • Baogang Liu
    Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, China.
  • Meisi Yan
    Department of Basic Medical Sciences, Harbin Medical University, Harbin, China.

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