The shared biomarkers and immune landscape in psoriatic arthritis and rheumatoid arthritis: Findings based on bioinformatics, machine learning and single-cell analysis.

Journal: PloS one
PMID:

Abstract

OBJECTIVE: Psoriatic arthritis (PsA) and rheumatoid arthritis (RA) are the most common types of inflammatory musculoskeletal disorders that share overlapping clinical features and complications. The aim of this study was to identify shared marker genes and mechanistic similarities between PsA and RA.

Authors

  • Kaiyi Zhou
    Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Siyu Luo
    Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Qinxiao Wang
    Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Sheng Fang
    Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.