Computer-aided diagnosis of distal metastasis in non-small cell lung cancer by low-dose CT based radiomics and deep learning signatures.

Journal: La Radiologia medica
PMID:

Abstract

BACKGROUND: This study aimed to develop and validate radiomics and deep learning (DL) signatures for predicting distal metastasis (DM) of non-small cell lung cancer (NSCLC) in low-dose computed tomography (LDCT).

Authors

  • Xiaoyi Song
    Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
  • Xiaobei Duan
    Department of Nuclear Medicine, Jiangmen Central Hospital, Jiangmen, Guangdong Province, 529030, PR China. Electronic address: 258573168@qq.com.
  • Xinghua He
    Department of Nuclear Medicine, the Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
  • Yubo Wang
    School of Life Science and Technology, Xidian University, Xi'an, China.
  • KunWei Li
    The Department of Radiology, The Fifth Affiliated Hospital Sun Yat-Sen University, NO.52 Meihuadong Street, Zhuhai, 519000, Guangdong Province, China.
  • Bangxuan Deng
    Department of Nuclear Medicine, the Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
  • XiangMeng Chen
    The Department of Radiology, Jiangmen Central Hospital/Affiliated Jiangmen Hospital of Sun Yat-Sen University, No. 23 Haibang Street, Jiangmen, 529000, Guangdong, China.
  • Ying Wang
    Key Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi 710062, China.
  • Man Li
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Hong Shan
    Department of head and neck oncology, The cancer centre of the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province 519000, PR China; Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province 519000, PR China.