The protective effects of bone morphogenetic protein-7 against epithelial injury and matrix metalloproteases upregulation induced by silica in vitro.

Journal: Human & experimental toxicology
PMID: 28838258

Abstract

OBJECTIVE: We investigate the effects of bone morphogenetic protein-7 (BMP-7) on models with silica-induced and macrophage-mediated fibrosis and its possible mechanisms in vitro.

Authors

  • D Liang
    1 School of Public Health, Capital Medical University, Beijing, China.
  • G An
    1 School of Public Health, Capital Medical University, Beijing, China.
  • Z Zhu
    1 School of Public Health, Capital Medical University, Beijing, China.
  • Y Wang
    1 School of Public Health, Capital Medical University, Beijing, China.
  • G Yang
    3 Oncology Minimally Invasive Interventional Center, Beijing Youan Hospital, Capital Medical University, Beijing, China.
  • X Li
    1 School of Public Health, Capital Medical University, Beijing, China.
  • P Niu
    1 School of Public Health, Capital Medical University, Beijing, China.
  • L Chen
    College of Computing, Georgia Institute of Technology, Atlanta, GA, USA.
  • L Tian
    1 School of Public Health, Capital Medical University, Beijing, China.

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