AIMC Topic: Hydroxyproline

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Single-Molecule SERS Discrimination of Proline from Hydroxyproline Assisted by a Deep Learning Model.

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Discriminating low-abundance hydroxylation is a crucial and unmet need for early disease diagnostics and therapeutic development due to the small hydroxyl group with 17.01 Da. While single-molecule surface-enhanced Raman spectroscopy (SERS) sensors c...

A Hybrid Deep Learning Model for Predicting Protein Hydroxylation Sites.

International journal of molecular sciences
Protein hydroxylation is one type of post-translational modifications (PTMs) playing critical roles in human diseases. It is known that protein sequence contains many uncharacterized residues of proline and lysine. The question that needs to be answe...