Development and Validation of Interpretable Machine Learning Models for Clinically Significant Prostate Cancer Diagnosis in Patients With Lesions of PI-RADS v2.1 Score ≥3.

Journal: Journal of magnetic resonance imaging : JMRI
PMID:

Abstract

BACKGROUND: For patients with PI-RADS v2.1 ≥ 3, prostate biopsy is strongly recommended. Due to the unsatisfactory positive rate of biopsy, improvements in clinically significant prostate cancer (csPCa) risk assessments are required.

Authors

  • Mingjian Ruan
    Department of Urology, Peking University First Hospital, Beijing, China.
  • Yi Liu
    Department of Interventional Therapy, Ningbo No. 2 Hospital, Ningbo, China.
  • Kaifeng Yao
    Department of Urology, Peking University First Hospital, Beijing, China.
  • Kexin Wang
    Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Yu Fan
    Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, 77030, TX, USA. YFan1@mdanderson.org.
  • Shiliang Wu
    Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education, School of Energy and Environment, Southeast University, Nanjing 210096, PR China.
  • XiaoYing Wang