Diastolic function assessment with four-dimensional flow cardiovascular magnetic resonance using automatic deep learning E/A ratio analysis.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
PMID:

Abstract

BACKGROUND: Diastolic left ventricular (LV) dysfunction is a powerful contributor to the symptoms and prognosis of patients with heart failure. In patients with depressed LV systolic function, the E/A ratio, the ratio between the peak early (E) and the peak late (A) transmitral flow velocity, is the first step to defining the grade of diastolic dysfunction. Doppler echocardiography (echo) is the preferred imaging technique for diastolic function assessment, while cardiovascular magnetic resonance (CMR) is less established as a method. Previous four-dimensional (4D) Flow-based studies have looked at the E/A ratio proximal to the mitral valve, requiring manual interaction. In this study, we compare an automated, deep learning-based and two semi-automated approaches for 4D Flow CMR-based E/A ratio assessment to conventional, gold-standard echo-based methods.

Authors

  • Federica Viola
    Division of Diagnostics and Specialist Medicine, Department of Health Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
  • Mariana Bustamante
    Division of Cardiovascular Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
  • Ann Bolger
    Division of Diagnostics and Specialist Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Department of Medicine, University of California San Francisco, San Francisco, CA, United States.
  • Jan Engvall
    Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
  • Tino Ebbers
    Division of Diagnostics and Specialist Medicine, Department of Health Medicine and Caring Sciences, Linköping University, Linköping, Sweden.