Combined brain topological metrics with machine learning to distinguish essential tremor and tremor-dominant Parkinson's disease.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
PMID:

Abstract

BACKGROUND: Essential tremor (ET) and Parkinson's disease (PD) are the two most prevalent movement disorders, sharing several overlapping tremor clinical features. Although growing evidence pointed out that changes in similar brain network nodes are associated with these two diseases, the brain network topological properties are still not very clear.

Authors

  • Pan Xiao
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
  • Qin Li
    Department of Spine Surgery, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.
  • Honge Gui
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
  • Bintao Xu
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
  • Xiaole Zhao
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
  • Hongyu Wang
    School of Information Science and Technology, Northwest University, Xi'an, Shaanxi, China.
  • Li Tao
    Molecular Imaging Instrumentation Laboratory, Stanford University, Stanford, United States of America.
  • Huiyue Chen
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
  • Hansheng Wang
    Guanghua School of Management, Peking University, Beijing, 100871, China.
  • Fajin Lv
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Tianyou Luo
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
  • Oumei Cheng
    Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Jin Luo
    Departments of Surgery, Stanford University, Stanford, CA 94305, USA.
  • Yun Man
    Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Zheng Xiao
    Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Weidong Fang
    Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China. fwd9707@sina.com.