Enhancing the prediction of symptomatic radiation pneumonitis for locally advanced non-small-cell lung cancer by combining 3D deep learning-derived imaging features with dose-volume metrics: a two-center study.

Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
PMID:

Abstract

OBJECTIVE: This study aims to examine the ability of deep learning (DL)-derived imaging features for the prediction of radiation pneumonitis (RP) in locally advanced non-small-cell lung cancer (LA-NSCLC) patients.

Authors

  • Yan Kong
    Computational Optics Laboratory, School of Science, Jiangnan University, Wuxi, Jiangsu, 214122, China.
  • Mingming Su
    Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, 214122, Wuxi, Jiangsu, China.
  • Yan Zhu
    Department of Chemistry, Xixi Campus, Zhejiang University, Hangzhou, 310028, China. Electronic address: zhuyan@zju.edu.cn.
  • Xuan Li
    College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, China.
  • Jinmeng Zhang
    Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, 214122, Wuxi, Jiangsu, China.
  • Wenchao Gu
    Department of Diagnostic and Interventional Radiology, University of Tsukuba, Ibaraki, Japan.
  • Fei Yang
    Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, University of South China, Hengyang 421001, China.
  • Jialiang Zhou
    Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, 214122, Wuxi, Jiangsu, China.
  • Jianjiao Ni
    Department of Radiation Oncology, Fudan University Shanghai Cancer Center, 270 Dongan Road, Xuhui, 200032, Shanghai, China.
  • Xi Yang
    Department of Health Outcomes and Biomedical Informatics.
  • Zhengfei Zhu
    Department of Radiation Oncology, Fudan University Shanghai Cancer Center, 270 Dongan Road, Xuhui, 200032, Shanghai, China. fuscczzf@163.com.
  • Jianfeng Huang
    Department of Radiation Oncology, Affiliated Hospital of Jiangnan University, 1000 Hefeng Road, 214122, Wuxi, Jiangsu, China. 9862019007@jiangnan.edu.cn.