Deep Learning for Automatic Gross Tumor Volumes Contouring in Esophageal Cancer Based on Contrast-Enhanced Computed Tomography Images: A Multi-Institutional Study.

Journal: International journal of radiation oncology, biology, physics
Published Date:

Abstract

PURPOSE: To develop and externally validate an automatic artificial intelligence (AI) tool for delineating gross tumor volume (GTV) in patients with esophageal squamous cell carcinoma (ESCC), which can assist in neo-adjuvant or radical radiation therapy treatment planning.

Authors

  • Shuaitong Zhang
    CAS Key Laboratory of Molecular Imaging, Institute of Automation, Beijing, 100190, China.
  • KunWei Li
    The Department of Radiology, The Fifth Affiliated Hospital Sun Yat-Sen University, NO.52 Meihuadong Street, Zhuhai, 519000, Guangdong Province, China.
  • Yuchen Sun
    School of Medical Technology, Beijing Institute of Technology, Beijing, China.
  • Yun Wan
    Department of Radiology, Xinyi City People's Hospital, Xinyi, Guangdong, China.
  • Yong Ao
    Department of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China; State Key Laboratory of Oncology in South China, Guangdong Esophageal Cancer Institute, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
  • Yinghua Zhong
    Department of Radiology, The Third People's Hospital of Zhuhai, Zhuhai, Guangdong, China.
  • Mingzhu Liang
    Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China.
  • Lizhu Wang
    Department of Radiology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China.
  • XiangMeng Chen
    The Department of Radiology, Jiangmen Central Hospital/Affiliated Jiangmen Hospital of Sun Yat-Sen University, No. 23 Haibang Street, Jiangmen, 529000, Guangdong, China.
  • Xiaofeng Pei
    Department of Radiation Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, China.
  • Yi Hu
    School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Duanduan Chen
    Phage Research Center of Liaocheng University, Liaocheng, China.
  • Man Li
    Department of Psychogeriatrics, Kangci Hospital of Jiaxing, Tongxiang, Zhejiang, China.
  • Hong Shan
    Department of head and neck oncology, The cancer centre of the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province 519000, PR China; Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province 519000, PR China.