A Randomized Phase 2 Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy-Induced Esophagitis During the Treatment of Lung Cancer: Results of NRG Oncology RTOG 1012.

Journal: International journal of radiation oncology, biology, physics
Published Date: Nov 23, 2016

Abstract

PURPOSE: Randomized trials have shown that honey is effective for the prevention of radiation-induced mucositis in head and neck cancer patients. Because there is no efficacious preventative for radiation esophagitis in lung cancer patients, this trial compared liquid honey, honey lozenges, and standard supportive care for radiation esophagitis.

Authors

  • Shannon E Fogh
    University of California San Francisco, San Francisco, California. Electronic address: Shannon.Fogh@ucsf.edu.
  • Snehal Deshmukh
    NRG Oncology Statistics and Data Management Center, Philadelphia, Pennsylvania.
  • Lawrence B Berk
    University of South Florida, Tampa, Florida.
  • Amylou C Dueck
    Mayo Clinic in Arizona, Scottsdale, Arizona.
  • Kevin Roof
    Southeast Cancer Control Consortium, Inc, CCOP, Winston-Salem, North Carolina.
  • Sherif Yacoub
    York Cancer Center, York, Pennsylvania.
  • Thomas Gergel
    Geisinger Medical Center CCOP, Danville, Pennsylvania.
  • Kevin Stephans
    Cleveland Clinic Foundation, Cleveland, Ohio.
  • Andreas Rimner
    Memorial Sloan Kettering Cancer Center, New York, New York.
  • Albert DeNittis
    Main Line CCOP, Wynnewood, Pennsylvania.
  • John Pablo
    Lewis Cancer & Research Pavilion at St. Joseph's/Candler, Savannah, Georgia.
  • Justin Rineer
    UF Health Cancer Center - Orlando Health, Orlando, Florida.
  • Terence M Williams
    Ohio State University Medical Center, Columbus, Ohio.
  • Deborah Bruner
    Emory University, Atlanta, Georgia.

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