AIMC Topic: Radiation Injuries

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Development and validation of a machine learning-based model for predicting radiation-induced hypothyroidism in nasopharyngeal carcinoma.

Radiation oncology (London, England)
BACKGROUND AND PURPOSE: This study aims to develop a robust and user-friendly prediction model for radiation-induced hypothyroidism (RIHT) in nasopharyngeal carcinoma (NPC) patients.

Machine learning-enhanced normal tissue complication probability modeling for late sciatic nerve toxicity prediction in carbon-ion radiotherapy: model development and clinical validation.

Physics in medicine and biology
To develop a machine learning-enhanced normal tissue complication probability (NTCP) model for predicting late sciatic nerve toxicity (LSNT) in sacrococcygeal chordoma (SC) and locally recurrent rectal cancer (LRRC) patients undergoing carbon-ion rad...

CNN-based prediction using early post-radiotherapy MRI as a proxy for toxicity in the murine head and neck.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Radiotherapy (RT) of head and neck cancer can cause severe toxicities. Early identification of individuals at risk could enable personalized treatment. This study evaluated whether convolutional neural networks (CNNs) applied ...

Prognostic models for radiation-induced complications after radiotherapy in head and neck cancer patients.

The Cochrane database of systematic reviews
BACKGROUND: Radiotherapy is the mainstay of treatment for head and neck cancer (HNC) but may induce various side effects on surrounding normal tissues. To reach an optimal balance between tumour control and toxicity prevention, normal tissue complica...

Radiation enteritis associated with temporal sequencing of total neoadjuvant therapy in locally advanced rectal cancer: a preliminary study.

Radiation oncology (London, England)
BACKGROUND: This study aimed to develop and validate a multi-temporal magnetic resonance imaging (MRI)-based delta-radiomics model to accurately predict severe acute radiation enteritis risk in patients undergoing total neoadjuvant therapy (TNT) for ...

A deep learning model for predicting radiation-induced xerostomia in patients with head and neck cancer based on multi-channel fusion.

BMC medical imaging
OBJECTIVES: Radiation-induced xerostomia is a common sequela in patients who undergo head and neck radiation therapy. This study aims to develop a three-dimensional deep learning model to predict xerostomia by fusing data from the gross tumor volume ...

Deep learning dosiomics in grade 4 radiation-induced lymphopenia prediction in radiotherapy for esophageal cancer: a multi-center study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: To investigate the feasibility and accuracy of using deep learning and dosiomics features, as well as their combination with dose-volume histogram (DVH) parameters and clinical factors to predict grade 4 radiation-induced lymphopenia (G4RIL)...

Study on the relationship between vaginal dose and radiation-induced vaginal injury following cervical cancer radiotherapy, and model development.

Frontiers in public health
OBJECTIVE: This study investigates the relationship between vaginal radiation dose and radiation-induced vaginal injury in cervical cancer patients, with the aim of developing a risk prediction model to support personalized treatment strategies.

Development and validation of Prediction models for radiation-induced hypoglossal neuropathy in patients with nasopharyngeal carcinoma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: To establish predictive models for radiation-induced hypoglossal neuropathy (RIHN) in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT).

Impact of harmonization on predicting complications in head and neck cancer after radiotherapy using MRI radiomics and machine learning techniques.

Medical physics
BACKGROUND: Variations in medical images specific to individual scanners restrict the use of radiomics in both clinical practice and research. To create reproducible and generalizable radiomics-based models for outcome prediction and assessment, data...