Machine learning for prediction of chronic kidney disease progression: Validation of the Klinrisk model in the CANVAS Program and CREDENCE trial.

Journal: Diabetes, obesity & metabolism
PMID:

Abstract

AIM: To validate the Klinrisk machine learning model for prediction of chronic kidney disease (CKD) progression in patients with type 2 diabetes in the pooled CANVAS/CREDENCE trials.

Authors

  • Navdeep Tangri
    Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.
  • Thomas W Ferguson
    Department of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
  • Ryan J Bamforth
    Chronic Disease Innovation Centre, Seven Oaks General Hospital, Winnipeg, Canada.
  • Silvia J Leon
    Chronic Disease Innovation Centre, Seven Oaks General Hospital, Winnipeg, Canada.
  • Clare Arnott
    The George Institute for Global Health, University of New South Wales, Sydney, Australia.
  • Kenneth W Mahaffey
    Stanford Center for Clinical Research, Stanford University School of Medicine, Stanford, CA.
  • Sradha Kotwal
    The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
  • Hiddo J L Heerspink
    Department of Clinical Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; The George Institute for Global Health, Sydney, Australia.
  • Vlado Perkovic
    The George Institute for Global Health, University of New South Wales Sydney, Sydney, Australia.
  • Robert A Fletcher
    Sensyne Health Plc, Schrodinger Building, Heatley Road, Oxford Science Park, Oxford, OX4 4GE, UK.
  • Brendon L Neuen
    The George Institute for Global Health, University of New South Wales, Sydney, Australia.