A clinical-radiomic-pathomic model for prognosis prediction in patients with hepatocellular carcinoma after radical resection.

Journal: Cancer medicine
Published Date: Jun 1, 2024

Abstract

PURPOSE: Radical surgery, the first-line treatment for patients with hepatocellular cancer (HCC), faces the dilemma of high early recurrence rates and the inability to predict effectively. We aim to develop and validate a multimodal model combining clinical, radiomics, and pathomics features to predict the risk of early recurrence.

Authors

  • Qu Xie
    Department of Hepato-Pancreato-Biliary & Gastric Medical Oncology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
  • Zeyin Zhao
    Department of Biomedical Informatics, College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
  • Yanzhen Yang
    Department of Hepato-Pancreato-Biliary & Gastric Medical Oncology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
  • Xiaohong Wang
    School of Reliability and Systems Engineering, Beihang University, Beijing 100191, China. wxhong@buaa.edu.cn.
  • Wei Wu
    Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
  • Haitao Jiang
    University of Science and Technology of China, No.96, JinZhai Road Baohe District,Hefei, Anhui 230026, PR China.
  • Weiyuan Hao
    Department of Intervention, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
  • Ruizi Peng
    Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan, 410082, China.
  • Cong Luo
    Department of Hepato-Pancreato-Biliary & Gastric Medical Oncology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.

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