AIMC Journal:
Biomedical chromatography : BMC

Showing 1 to 8 of 8 articles

Mass Spectrometry-Based Chromatographic and Computational Workflows for Biomarker and Therapeutic Target Discovery: A Comprehensive Review.

Biomedical chromatography : BMC Sep 1, 2026
The identification of biomarkers and therapeutic targets is essential to the success of precision medicine. However, to reliably identify them, one must employ a combination of analytical and computational methods. This article describes the importan...
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Analytical Quality by Design-Based Reverse-Phase High-Performance Liquid Chromatography Method Development for Biomarker: A Comprehensive Review of Quality Assessment and Analytical Trends.

Biomedical chromatography : BMC Sep 1, 2026
Biomarkers play a crucial role in disease diagnosis and therapeutic monitoring, necessitating the development of reliable and robust analytical methods. Reverse-phase high-performance liquid chromatography (RP-HPLC) is widely employed for biomarker a...
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Emerging Trends and Advancements in HPLC Technique: The Role of Nanotechnology, Machine Learning, and AI Optimization.

Biomedical chromatography : BMC Aug 1, 2026
High-performance liquid chromatography (HPLC) plays a central role in pharmaceutical and biomedical analysis owing to its exceptional separation efficiency, sensitivity, and versatility. It plays a crucial role in the separation, identification, and ...
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Combining Online HPLC-ABTS Screening With Machine Learning to Predict the Bioactivity of Antioxidant Components in Pandani Tectorii Radix et Rhizoma.

Biomedical chromatography : BMC Jul 1, 2026
This study developed an online HPLC-ABTS method to screen antioxidant phenolic acids in Pandani tectorii radix et rhizoma (PT) from 20 geographical origins. Six common constituents were screened and assigned by standards: neochlorogenic acid, chlorog...
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Integrated Experimental and Computational Evaluation of the Gut-Targeted Anticoccidial Potential of Agaricus bisporus Methanolic Extract.

Biomedical chromatography : BMC Jun 1, 2026
Coccidiosis caused by Eimeria spp. is a major constraint to global poultry production, causing economic losses exceeding USD 13 billion annually. Growing drug resistance from prolonged anticoccidial use highlights the need for safer, eco-friendly alt...
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Integrative LC-MS/MS, Bioinformatics, and Molecular Dynamics Reveal Multitarget Antioxidant Mechanisms of Bushen Huoxue Decoction in Intervertebral Disc Degeneration.

Biomedical chromatography : BMC Feb 1, 2026
Intervertebral disc degeneration (IVDD) is a major cause of low back pain and disability. Excessive reactive oxygen species (ROS) disrupt disc homeostasis. Bushen Huoxue (BSHX) decoction, a traditional Chinese medicine, shows clinical efficacy in IVD...
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A Comprehensive Review of Analytical Techniques for Doxycycline and Its Metabolites.

Biomedical chromatography : BMC Feb 1, 2026
Doxycycline (DC), a second-generation tetracycline antibiotic, is extensively used in human and veterinary medicine for its broad-spectrum activity, favorable pharmacokinetics, and high bioavailability. This review focuses on analytical methods for d...
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Integration of Metabolomics, Lipidomics, and Machine Learning for Developing a Biomarker Panel to Distinguish the Severity of Metabolic-Associated Fatty Liver Disease.

Biomedical chromatography : BMC Jul 1, 2025
Metabolic-associated fatty liver disease (MAFLD), a global health challenge linked to metabolic syndrome, requires accurate severity stratification for clinical management. Current invasive diagnostic methods limit practical implementation. This stud...
Humans Machine Learning Biomarkers Female Adult Male Middle Aged Severity of Illness Index Fatty Liver Metabolomics Chromatography, Liquid Tandem Mass Spectrometry Lipidomics
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