AIMC Topic: Fatty Liver
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Liver MRI proton density fat fraction inference from contrast enhanced CT images using deep learning: A proof-of-concept study.
PloS one
Aug 8, 2025
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease worldwide, affecting over 30% of the global general population. Its progressive nature and association with other chronic diseases make...
Innovative machine learning approach for liver fibrosis and disease severity evaluation in MAFLD patients using MRI fat content analysis.
Clinical and experimental medicine
Aug 5, 2025
This study employed machine learning models to quantitatively analyze liver fat content from MRI images for the evaluation of liver fibrosis and disease severity in patients with metabolic dysfunction-associated fatty liver disease (MAFLD). A total o...
Markers of body fat, the mediating role of alanine aminotransferase, and their association with the risk of metabolic dysfunction-associated steatotic liver disease.
European journal of pediatrics
Aug 2, 2025
Metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity correlates with metabolic dysfunction, yet interactions between anthropometrics, liver enzymes, and risk of MASLD remain unclear. This study included 219 childr...
Development of a novel deep learning method that transforms tabular input variables into images for the prediction of SLD.
Scientific reports
Jul 31, 2025
Steatotic liver disease (SLD), formerly named fatty liver disease, has a prevalence estimated at 30-38% in adults. Detection of SLD is important, since prompt initiation of treatment can stop disease progression, lead to a reduction in adverse outcom...
Machine learning models using non-invasive tests & B-mode ultrasound to predict liver-related outcomes in metabolic dysfunction-associated steatotic liver disease.
Scientific reports
Jul 8, 2025
Advanced metabolic-dysfunction-associated steatotic liver disease (MASLD) fibrosis (F3-4) predicts liver-related outcomes. Serum and elastography-based non-invasive tests (NIT) cannot yet reliably predict MASLD outcomes. The role of B-mode ultrasound...
Therapeutic horizons in metabolic dysfunction-associated steatohepatitis.
The Journal of clinical investigation
Jul 1, 2025
Metabolic dysfunction-associated steatohepatitis (MASH), the progressive inflammatory form of MASLD, is now a leading cause of chronic liver disease worldwide. Driven by obesity and type 2 diabetes, MASH significantly increases the risk of cirrhosis,...
The utility of an artificial intelligence model based on decision tree and evolution algorithm to evaluate steatotic liver disease in a primary care setting.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Jun 16, 2025
Many ways of classifying steatotic liver disease (SLD) with metabolic conditions have been proposed. Thus, SLD-related variables were verified using a decision tree. We tested if the suggested components of the actual classification (metabolic dysfun...
Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH.
Gut microbes
May 21, 2025
Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). We analyzed microbiomes of obese children with and w...
Unsupervised Test-Time Adaptation for Hepatic Steatosis Grading Using Ultrasound B-Mode Images.
IEEE transactions on ultrasonics, ferroelectrics, and frequency control
May 7, 2025
Ultrasound (US) is considered a key modality for the clinical assessment of hepatic steatosis (i.e., fatty liver) due to its noninvasiveness and availability. Deep learning methods have attracted considerable interest in this field, as they are capab...
Unraveling MASLD: The Role of Gut Microbiota, Dietary Modulation, and AI-Driven Lifestyle Interventions.
Nutrients
May 4, 2025
Gut microbiota has a crucial role in the pathophysiology of metabolic-associated steatotic liver disease (MASLD), influencing various metabolic mechanisms and contributing to the development of the disease. Dietary interventions targeting gut microbi...
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