Cytometry. Part A : the journal of the International Society for Analytical Cytology
Nov 19, 2020
Deep learning is rapidly becoming the technique of choice for automated segmentation of nuclei in biological image analysis workflows. In order to evaluate the feasibility of training nuclear segmentation models on small, custom annotated image datas...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jun 30, 2020
The application of machine learning and artificial intelligence to high-dimensional cytometry data sets has increasingly become a staple of bioinformatic data analysis over the past decade. This is especially true in the field of cancer biology, wher...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jun 9, 2020
The wealth of information captured by multiparameter flow cytometry (MFC) can be analyzed by recent methods of computer vision when represented as a single image file. We therefore transformed MFC raw data into a multicolor 2D image by a self-organiz...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 24, 2020
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. While there are a number of well-recognized prognostic biomarkers at diagnosis, the most powerful independent prognostic factor is the response of the leukemia to induction chemo...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Feb 10, 2020
Cell image classification methods are currently being used in numerous applications in cell biology and medicine. Applications include understanding the effects of genes and drugs in screening experiments, understanding the role and subcellular local...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Jan 25, 2020
Optical imaging technology that has the advantages of high sensitivity and cost-effectiveness greatly promotes the progress of nondestructive single-cell studies. Complex cellular image analysis tasks such as three-dimensional reconstruction call for...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Dec 6, 2019
Understanding the intricacies of particle-cell interactions is essential for many applications such as imaging, phototherapy, and drug/gene delivery, because it is the key to accurate control of the particle properties for the improvement of their th...