AI Medical Compendium Journal:
International journal of biological macromolecules

Showing 1 to 10 of 120 articles

m6A-SPP: Identification of RNA N6-methyladenosine modification sites through multi-source biological features and a hybrid deep learning architecture.

International journal of biological macromolecules
The N6-methyladenosine(m6A) modification plays crucial regulatory roles in various biological processes including gene expression regulation, RNA stability, splicing, and translation. Accurate prediction of m6A modification sites is essential for und...

Artificial neural network-based fungal chitin production for submicron-chitosan synthesis: effects on bioremediation for heavy metal pollution.

International journal of biological macromolecules
This study focused on optimizing fungal chitin (CT) production from a newly identified Fusarium incarnatum (GenBank: OL314753) for subsequent synthesis of submicron chitosan (sm-CS) tailored for enhanced heavy metal removal. Initial attempts to optim...

Adsorptive removal of heavy metal ions from wastewater using shrimp chitosan-cysteine-glutaraldehyde hydrogel as a sustainable biosorbent.

International journal of biological macromolecules
A new biosorbent, crosslinked chitosan-cysteine-glutaraldehyde hydrogel (CSCys-HG), was successfully synthesized and characterized using microanalytical and spectroscopic methods. CSCys-HG exhibited a high gel fraction and swelling capacity, indicati...

Inhibition mechanism of α-amylase and amyloglucosidase by spherical nanocrystalline cellulose with varying particle sizes.

International journal of biological macromolecules
In this study, spherical nanocrystalline cellulose (SNC) was isolated from native cellulose through phosphoric acid hydrolysis and ultrasonic treatment. The spherical nanocrystalline cellulose with three particle sizes of 50 nm, 60 nm and 70 nm was s...

Impact of dielectric barrier discharge cold plasma on Dendrobium officinale polysaccharides: Physicochemical and functional properties.

International journal of biological macromolecules
Dendrobium officinale has garnered significant attention due to its notable bioactivity and health benefits. The polysaccharide extracted from Dendrobium officinale (DOP) is the primary source of its functionality. However, its poor solubility and hi...

A sulfated fucopyranosyl-glucosamino-glucopyranose from marine heterotrophic Bacillus tequilensis regulates inflammatory cytokines in lipopolysaccharide-stimulated human monocyte THP-1 cells.

International journal of biological macromolecules
Marine macroalga or seaweed-associated bacterial exopolysaccharides, particularly (1 → 3)-linked β-glucans, possess potential ability to reduce inflammatory responses by targeting various cytokines. In this direction, a sulfated exopolysaccharide (BP...

Integrative PPI network and random forest analysis identifies KIF4A, TOP2A, and ASPM protein macromolecules as novel protein biomarkers in renal carcinoma pathogenesis.

International journal of biological macromolecules
The pathogenesis of kidney cancer is not fully understood, so there is an urgent need to identify new biomarkers to improve diagnosis and treatment. The study identified KIF4A, TOP2A and ASPM as novel protein biomarkers for renal cancer and explored ...

Microencapsulation of Lactobacillus cells utilizing the β-glucan-rich cell wall of Saccharomyces cerevisiae for enhanced stability and efficacy.

International journal of biological macromolecules
Probiotic encapsulation enhances bacterial stability and viability, yet conventional materials like sodium alginate have limitations, particularly in acidic environments. This study explores the use of β-glucan-rich Saccharomyces cerevisiae cell wall...

Assessing amyloid fibrils and amorphous aggregates: A review.

International journal of biological macromolecules
Protein misfolding and aggregation play a central role in the progression of neurodegenerative diseases such as Alzheimer's and Parkinson's. These aggregates manifest either as structured amyloid fibrils enriched in β-sheet conformations or as irregu...