AI Medical Compendium Journal:
Journal of clinical pharmacy and therapeutics

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Development of LC-MS/MS determination method and backpropagation artificial neural networks pharmacokinetic model of febuxostat in healthy subjects.

Journal of clinical pharmacy and therapeutics Nov 17, 2020
WHAT IS KNOWN AND OBJECTIVE: Febuxostat is a well-known drug for treating hyperuricemia and gout. The published methods for determination of febuxostat in human plasma might be unsuitable for high-throughput determination and widespread application. ...
Humans Neural Networks, Computer Reproducibility of Results Chromatography, Liquid Area Under Curve Febuxostat Gout Suppressants Tandem Mass Spectrometry Healthy Volunteers Half-Life Drug Stability Metabolic Clearance Rate
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Similarity-based machine learning support vector machine predictor of drug-drug interactions with improved accuracies.

Journal of clinical pharmacy and therapeutics Dec 18, 2018
WHAT IS KNOWN AND OBJECTIVE: Drug-drug interactions (DDI) are frequent causes of adverse clinical drug reactions. Efforts have been directed at the early stage to achieve accurate identification of DDI for drug safety assessments, including the devel...
Humans Machine Learning Databases, Factual Computer Simulation Reproducibility of Results Support Vector Machine Drug Interactions Drug-Related Side Effects and Adverse Reactions Pharmacovigilance
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