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Acetyl-CoA Carboxylase

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Combined structure-based virtual screening and machine learning approach for the identification of potential dual inhibitors of ACC and DGAT2.

International journal of biological macromolecules 39089556
Acetyl-coenzyme A carboxylase (ACC) and diacylglycerol acyltransferase 2 (DGAT2) are recognized as potential therapeutic targets for nonalcoholic fatty liver disease (NAFLD). Inhibitors targeting ACC and DGAT2 have exhibited the capacity to reduce he...
Acetyl-CoA Carboxylase Binding Sites Diacylglycerol O-Acyltransferase Drug Evaluation, Preclinical Enzyme Inhibitors Humans Machine Learning Molecular Docking Simulation Molecular Dynamics Simulation Non-alcoholic Fatty Liver Disease Protein Binding
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