AIMC Topic: Amino Acid Sequence

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A novel fractal approach for predicting G-protein-coupled receptors and their subfamilies with support vector machines.

Bio-medical materials and engineering
G-protein-coupled receptors (GPCRs) are seven membrane-spanning proteins and regulate many important physiological processes, such as vision, neurotransmission, immune response and so on. GPCRs-related pathways are the targets of a large number of ma...

Sequence-based protein superfamily classification using computational intelligence techniques: a review.

International journal of data mining and bioinformatics
Protein superfamily classification deals with the problem of predicting the family membership of newly discovered amino acid sequence. Although many trivial alignment methods are already developed by previous researchers, but the present trend demand...

Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.

Methods in molecular biology (Clifton, N.J.)
Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in CPP-based research, demonstrating the potential of CPPs as therapeutic candidates. In the past, man...

Artificial neural networks for dihedral angles prediction in enzyme loops: a novel approach.

International journal of bioinformatics research and applications
Structure prediction of proteins is considered a limiting step and determining factor in drug development and in the introduction of new therapies. Since the 3D structures of proteins determine their functionalities, prediction of dihedral angles rem...