AIMC Topic: Bioreactors

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Optimization of operational parameters using RSM, ANN, and SVM in membrane integrated with rotating biological contactor.

Chemosphere
Membrane fouling is a critical bottleneck to the widespread adoption of membrane separation processes. It diminishes the membrane permeability and results in high operational energy costs. The current study presents optimizing the operating parameter...

Machine learning-based model construction and identification of dominant factor for simultaneous sulfide and nitrate removal process.

Bioresource technology
Accurate water quality prediction models are essential for the successful implementation of the simultaneous sulfide and nitrate removal process (SSNR). Traditional models, such as regression and analysis of variance, do not provide accurate predicti...

Optimization of biogas production from straw wastes by different pretreatments: Progress, challenges, and prospects.

The Science of the total environment
Lignocellulosic biomass (LCB) presents a promising feedstock for carbon management due to enormous potential for achieving carbon neutrality and delivering substantial environmental and economic benefit. Bioenergy derived from LCB accounts for about ...

Saline wastewater treatment by bioelectrochemical process (BEC) based on Al-electrocoagulation and halophilic bacteria: optimization using ANN with new approach.

Environmental technology
In the present study, a bioelectrochemical reactor (BEC) was utilized to treat two types of real saline produced water (PW). BEC was designed based on the combination of electrocoagulation (EC) process with halophilic microorganisms, and it was asses...

Enhancing corn stalk-based anaerobic digestion with different types of zero-valent iron added during the acidification stage: Performance and mechanism.

Journal of environmental sciences (China)
Anaerobic digestion has been defined as a competitive approach to facilitate the recycling of corn stalks. However, few studies have focused on the role of direct interspecies electron transfer (DIET) pathway in the acidification stage under the addi...

The monitoring of oil production process by deep learning based on morphology in oleaginous yeasts.

Applied microbiology and biotechnology
BACKGROUND: Monitoring jar fermenter-cultured microorganisms in real time is important for controlling productivity of bioproducts in large-scale cultivation settings. Morphological data is used to understand the growth and fermentation states of the...

Applications of artificial intelligence in anaerobic co-digestion: Recent advances and prospects.

Bioresource technology
Anaerobic co-digestion (AcoD) offers several merits such as better digestibility and process stability while enhancing methane yield due to synergistic effects. Operation of an efficient AcoD system, however, requires full comprehension of important ...

Global stability of a continuous bioreactor model under persistent variation of the dilution rate.

Mathematical biosciences and engineering : MBE
In this work, the global stability of a continuous bioreactor model is studied, with the concentrations of biomass and substrate as state variables, a general non-monotonic function of substrate concentration for the specific growth rate, and constan...

CPV of the Future: AI-Powered Continued Process Verification for Bioreactor Processes.

PDA journal of pharmaceutical science and technology
According to the standard guidelines by the FDA, process validation in biopharma manufacturing encompasses a life cycle consisting of three stages: process design (PD), process qualification (PQ), and continued process verification (CPV). The validit...

Continuous biomanufacturing with microbes - upstream progresses and challenges.

Current opinion in biotechnology
Current biomanufacturing facilities are mainly built for batch or fed-batch operations, which are subject to low productivities and do not achieve the great bioconversion potential of the rewired cells generated via modern biotechnology. Continuous b...