AIMC Topic: Blood Proteins

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Proteomics Analysis of FLT3-ITD Mutation in Acute Myeloid Leukemia Using Deep Learning Neural Network.

Annals of clinical and laboratory science Jan 1, 2019
Deep Learning can significantly benefit cancer proteomics and genomics. In this study, we attempted to determine a set of critical proteins that were associated with the FLT3-ITD mutation in newly-diagnosed acute myeloid leukemia patients. A Deep Lea...
Humans Neural Networks, Computer Leukemia, Myeloid, Acute Deep Learning Proteomics Proteome Blood Proteins Mutation Tandem Repeat Sequences fms-Like Tyrosine Kinase 3
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Prediction of Drug-Plasma Protein Binding Using Artificial Intelligence Based Algorithms.

Combinatorial chemistry & high throughput screening Jan 1, 2018
AIM AND OBJECTIVE: Plasma protein binding (PPB) has vital importance in the characterization of drug distribution in the systemic circulation. Unfavorable PPB can pose a negative effect on clinical development of promising drug candidates. The drug d...
Humans Artificial Intelligence Algorithms Drug Design Blood Proteins Least-Squares Analysis Pharmaceutical Preparations Binding Sites
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