AIMC Topic: Buprenorphine, Naloxone Drug Combination

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Predictability of buprenorphine-naloxone treatment retention: A multi-site analysis combining electronic health records and machine learning.

Addiction (Abingdon, England) Jun 24, 2024
BACKGROUND AND AIMS: Opioid use disorder (OUD) and opioid dependence lead to significant morbidity and mortality, yet treatment retention, crucial for the effectiveness of medications like buprenorphine-naloxone, remains unpredictable. Our objective ...
Humans Machine Learning Retrospective Studies Electronic Health Records Female Adult Male Middle Aged Opioid-Related Disorders Narcotic Antagonists Opiate Substitution Treatment Buprenorphine, Naloxone Drug Combination
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Machine Learning-Driven Analysis of Individualized Treatment Effects Comparing Buprenorphine and Naltrexone in Opioid Use Disorder Relapse Prevention.

Journal of addiction medicine May 22, 2024
OBJECTIVE: A trial comparing extended-release naltrexone and sublingual buprenorphine-naloxone demonstrated higher relapse rates in individuals randomized to extended-release naltrexone. The effectiveness of treatment might vary based on patient char...
Humans Machine Learning Precision Medicine Female Adult Male Middle Aged Opioid-Related Disorders Delayed-Action Preparations Buprenorphine Narcotic Antagonists Opiate Substitution Treatment Secondary Prevention Naltrexone Buprenorphine, Naloxone Drug Combination
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