AIMC Topic: Computer Simulation

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Reinforcement learning for automated method development in liquid chromatography: insights in the reward scheme and experimental budget selection.

Journal of chromatography. A
Chromatographic problem solving, commonly referred to as method development (MD), is hugely complex, given the many operational parameters that must be optimized and their large effect on the elution times of individual sample compounds. Recently, th...

Overcoming methodological barriers in electronic nose clinical studies, a simulation data-based approach.

Journal of breath research
Analysis of volatile organic compounds by electronic nose (e-nose) may address gaps in non-invasive screening for neoplasia. Machine learning impacts study design and sample size requirements, but guidance on clinical study design is limited. This st...

Bioinspired adaptive visual servoing control for quadrotors.

Bioinspiration & biomimetics
Since every flight ends in a landing and every landing is a potential crash, deceleration during landing is one of the most critical flying maneuvers. Here we implement a recently-discovered insect visual-guided landing strategy in which the divergen...

Machine learning assisted in Silico discovery and optimization of small molecule inhibitors targeting the Nipah virus glycoprotein.

Scientific reports
The Nipah virus (NiV), a lethal pathogen from the Paramyxoviridae family, presents a significant global health threat as a result of its high mortality rate and inter-human transmission. This investigation employed in silico methods that were assiste...

How Effective Are Machine Learning and Doubly Robust Estimators in Incorporating High-Dimensional Proxies to Reduce Residual Confounding?

Pharmacoepidemiology and drug safety
BACKGROUND: Residual confounding presents a persistent challenge in observational studies, particularly in high-dimensional settings. High-dimensional proxy adjustment methods, such as the high-dimensional propensity score (hdPS), are widely used to ...

A classification-occupancy model based on automatically identified species data.

Ecology
Occupancy models estimate a species' occupancy probability while accounting for imperfect detection, but often overlook the issue of false-positive detections. This problem of false positives has gained attention recently with the rapid advancement o...

Adaptive Dynamic Surface Control of Epileptor Model Based on Nonlinear Luenberger State Observer.

International journal of neural systems
Epilepsy is a prevalent neurological disorder characterized by recurrent seizures, which are sudden bursts of electrical activity in the brain. The Epileptor model is a computational model specifically created to replicate the complex dynamics of epi...

The value of simulation testing for the evaluation of ambient digital scribes: a case report.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: The objective of this work is to demonstrate the value of simulation testing for rapidly evaluating artificial intelligence (AI) products.

Predicting Milk Flow Behavior in Human Lactating Breast: An Integrated Machine Learning and Computational Fluid Dynamics Approach.

Journal of biomechanical engineering
This study develops a comprehensive framework that integrates computational fluid dynamics (CFD) and machine learning (ML) to predict milk flow behavior in lactating breasts. Utilizing CFD and other high-fidelity simulation techniques to tackle fluid...

Distributed Synaptic Connection Strength Changes Dynamics in a Population Firing Rate Model in Response to Continuous External Stimuli.

Neural computation
Neural network complexity allows for diverse neuronal population dynamics and realizes higherorder brain functions such as cognition and memory. Complexity is enhanced through chemical synapses with exponentially decaying conductance and greater vari...