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Cytopathogenic Effect, Viral

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Differentiation of Cytopathic Effects (CPE) induced by influenza virus infection using deep Convolutional Neural Networks (CNN).

PLoS computational biology
Cell culture remains as the golden standard for primary isolation of viruses in clinical specimens. In the current practice, researchers have to recognize the cytopathic effects (CPE) induced by virus infection and subsequently use virus-specific mon...

A versatile automated pipeline for quantifying virus infectivity by label-free light microscopy and artificial intelligence.

Nature communications
Virus infectivity is traditionally determined by endpoint titration in cell cultures, and requires complex processing steps and human annotation. Here we developed an artificial intelligence (AI)-powered automated framework for ready detection of vir...

Cytopathic Effect Detection and Clonal Selection using Deep Learning.

Pharmaceutical research
PURPOSE: In biotechnology, microscopic cell imaging is often used to identify and analyze cell morphology and cell state for a variety of applications. For example, microscopy can be used to detect the presence of cytopathic effects (CPE) in cell cul...

A web-based artificial intelligence system for label-free virus classification and detection of cytopathic effects.

Scientific reports
Identifying viral replication within cells demands labor-intensive isolation methods, requiring specialized personnel and additional confirmatory tests. To facilitate this process, we developed an AI-powered automated system called AI Recognition of ...