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Vero Cells

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A Preliminary Investigation on the Antiviral Activities of the Philippine Marshmint (Mentha arvensis) Leaf Extracts against Dengue Virus Serotype 2 In Vitro.

The Kobe journal of medical sciences
In this study, we investigated the antiviral activity of lyophilized crude leaf extracts of the Philippine marshmint (Mentha arvensis L., commonly called yerba buena) against DENV-2 in vitro. The plant specimen was authenticated by DNA barcoding anal...

Alantolactone exhibited anti-herpes simplex virus 1 (HSV-1) action in vitro.

Bioscience trends
The aim of this study was to determine the inhibitory action of alantolactone, a gradient of traditional Chinese medicine Inulae Radix (Tu-Mu-Xiang), on herpes simplex virus 1 (HSV-1). African green monkey kidney cells (Vero cells) were infected with...

Experimental Data Based Machine Learning Classification Models with Predictive Ability to Select in Vitro Active Antiviral and Non-Toxic Essential Oils.

Molecules (Basel, Switzerland)
In the last decade essential oils have attracted scientists with a constant increase rate of more than 7% as witnessed by almost 5000 articles. Among the prominent studies essential oils are investigated as antibacterial agents alone or in combinatio...

Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2.

Viruses
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes COVID-19 and is responsible for the ongoing pandemic. Screening of potential antiviral drugs against SARS-CoV-2 depend on in vitro experiments, which are based on the quantification ...

Rapid and sensitive mycoplasma detection system using image-based deep learning.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
A major concern in the clinical application of cell therapy is the manufacturing cost of cell products, which mainly depends on quality control. The mycoplasma test, an important biological test in cell therapy, takes several weeks to detect a microo...

A versatile automated pipeline for quantifying virus infectivity by label-free light microscopy and artificial intelligence.

Nature communications
Virus infectivity is traditionally determined by endpoint titration in cell cultures, and requires complex processing steps and human annotation. Here we developed an artificial intelligence (AI)-powered automated framework for ready detection of vir...

Large-scale deep learning identifies the antiviral potential of PKI-179 and MTI-31 against coronaviruses.

Antiviral research
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to the global pandemic of Coronavirus Disease (2019) (COVID-19), underscoring the urgency for effective antiviral drugs. Despite the development of different vaccination strategies,...

A web-based artificial intelligence system for label-free virus classification and detection of cytopathic effects.

Scientific reports
Identifying viral replication within cells demands labor-intensive isolation methods, requiring specialized personnel and additional confirmatory tests. To facilitate this process, we developed an AI-powered automated system called AI Recognition of ...