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Extensively Drug-Resistant Tuberculosis

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Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction.

EBioMedicine 31047860
BACKGROUND: The diagnosis of multidrug resistant and extensively drug resistant tuberculosis is a global health priority. Whole genome sequencing of clinical Mycobacterium tuberculosis isolates promises to circumvent the long wait times and limited s...
Antitubercular Agents Cluster Analysis Computational Biology Databases, Genetic Evolution, Molecular Extensively Drug-Resistant Tuberculosis Genetic Variation Genome, Bacterial Genomics Humans Machine Learning Microbial Sensitivity Tests Models, Statistical Mycobacterium tuberculosis Prognosis Reproducibility of Results ROC Curve Tuberculosis, Multidrug-Resistant
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Machine learning investigation of tuberculosis with medicine immunity impact.

Diagnostic microbiology and infectious disease 39146634
Tuberculosis (T.B.) remains a prominent global cause of health challenges and death, exacerbated by drug-resistant strains such as multidrug-resistant tuberculosis MDR-TB and extensively drug-resistant tuberculosis XDR-TB. For an effective disease ma...
Antitubercular Agents Extensively Drug-Resistant Tuberculosis Humans Machine Learning Mycobacterium tuberculosis Tuberculosis Tuberculosis, Multidrug-Resistant
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