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Fluvastatin

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Spectrophotometric method for simultaneous determination of valsartan and substances from the group of statins in binary mixtures.

Acta pharmaceutica (Zagreb, Croatia)
Applicability of derivative spectrophotometry for the determination of valsartan in the presence of a substance from the group of statins was checked. The obtained results indicate that the proposed method may be effective by using appropriate deriva...

Application of molecular dynamics-based pharmacophore and machine learning approaches to identify novel Mcl1 inhibitors through drug repurposing and mechanics research.

Physical chemistry chemical physics : PCCP
Myeloid cell leukemia 1 (Mcl1), a critical protein that regulates apoptosis, has been considered as a promising target for antitumor drugs. The conventional pharmacophore screening approach has limitations in conformation sampling and data mining. He...