AIMC Topic: Fluvastatin

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Application of molecular dynamics-based pharmacophore and machine learning approaches to identify novel Mcl1 inhibitors through drug repurposing and mechanics research.

Physical chemistry chemical physics : PCCP Jun 6, 2024
Myeloid cell leukemia 1 (Mcl1), a critical protein that regulates apoptosis, has been considered as a promising target for antitumor drugs. The conventional pharmacophore screening approach has limitations in conformation sampling and data mining. He...
Humans Machine Learning Antineoplastic Agents Cell Line, Tumor Drug Repositioning Molecular Dynamics Simulation Quantum Theory Fluvastatin Myeloid Cell Leukemia Sequence 1 Protein Pharmacophore
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Spectrophotometric method for simultaneous determination of valsartan and substances from the group of statins in binary mixtures.

Acta pharmaceutica (Zagreb, Croatia) Dec 20, 2017
Applicability of derivative spectrophotometry for the determination of valsartan in the presence of a substance from the group of statins was checked. The obtained results indicate that the proposed method may be effective by using appropriate deriva...
Reproducibility of Results Sensitivity and Specificity Indoles Valsartan Hydroxymethylglutaryl-CoA Reductase Inhibitors Atorvastatin Fatty Acids, Monounsaturated Fluvastatin Pravastatin Spectrophotometry
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