AIMC Topic: Indoles

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Self-Assembly MXene/PDA@Cotton Fabric Pressure Sensor Integrated with Deep Learning for Sign Language Recognition.

ACS applied materials & interfaces
In recent years, smart textiles and flexible wearable products have garnered significant attention in fields such as human-computer interaction, medical rehabilitation training, and motion monitoring. Flexible pressure sensors have attracted signific...

AI based natural inhibitor targeting RPS20 for colorectal cancer treatment using integrated computational approaches.

Scientific reports
The increasing global incidence of cancer emphasizes the vital role of machine learning algorithms and artificial intelligence (AI) in identifying novel anticancer targets and developing new drugs. Computational approaches can significantly quicken r...

Synergistic application of artificial intelligence and response surface methodology for predicting and enhancing in vitro tuber production of potato (Solanum tuberosum).

PloS one
In vitro regeneration of potato tubers is highly significant in modern agriculture as it offers efficient propagation, genetic enhancement, and pathogen-free seed production. This study aimed to optimize in vitro tuberization by manipulating key vari...

Discrimination of Respiratory Tract Infections by a Reduced Graphene Oxide Array Modified with Metal-Organic Frameworks and Metal Phthalocyanines.

ACS nano
As a prevalent clinical condition, it is critical to distinguish between bacterial and viral respiratory tract infections given their pivotal role in guiding appropriate pharmaceutical interventions and preventing antibiotic misuse. Exhaled breath (E...

Artificial intelligence-enabled microsphere imaging immunosensor based on magnetic metal-organic frameworks-assisted sample pretreatment for detecting aflatoxin B in peanuts.

Journal of hazardous materials
Sensitive and rapid detection of aflatoxin B (AFB) is vital for safeguarding food safety, considering its potent carcinogenic toxicity. Herein, an artificial intelligence-enabled microsphere imaging (AI-MI) immunosensor based on magnetic metal-organi...

Predicting the anticancer activity of indole derivatives: A novel GP-tree-based QSAR model optimized by ALO with insights from molecular docking and decision-making methods.

Computers in biology and medicine
Indole derivatives have demonstrated significant potential as anticancer agents; however, the complexity of their structure-activity relationships and the high dimensionality of molecular descriptors present challenges in the drug discovery process. ...

AlgaeSperm: Microalgae-Based Soft Magnetic Microrobots for Targeted Tumor Treatment.

Small (Weinheim an der Bergstrasse, Germany)
Magnetic microrobots are significant platforms for targeted drug delivery, among which sperm-inspired types have attracted much attention due to their flexible undulation. However, mass production of sperm-like soft magnetic microrobots with high-spe...

Deep Learning Used with a Colorimetric Sensor Array to Detect Indole for Nondestructive Monitoring of Shrimp Freshness.

ACS applied materials & interfaces
Intelligent colorimetric freshness indicator is a low-cost way to intuitively monitor the freshness of fresh food. A colorimetric strip sensor array was prepared by -dimethylaminocinnamaldehyde (PDL)-doped poly(vinyl alcohol) (PVA) and chitosan (Chit...

Artificial Intelligence in Decrypting Cytoprotective Activity under Oxidative Stress from Molecular Structure.

International journal of molecular sciences
Artificial intelligence (AI) is widely explored nowadays, and it gives opportunities to enhance classical approaches in QSAR studies. The aim of this study was to investigate the cytoprotective activity parameter under oxidative stress conditions for...

Research progress on the structure and biological diversities of 2-phenylindole derivatives in recent 20 years.

Bioorganic chemistry
The privileged structure binds to multiple receptors with high affinity, which is helpful to the development of new bioactive compounds. Indole is classified as a privileged structure, which may be one of the most important structural categories in d...