AIMC Topic: HIV Envelope Protein gp41

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Utilizing Machine Learning to Improve Neutralization Potency of an HIV-1 Antibody Targeting the gp41 N-Heptad Repeat.

ACS chemical biology Jul 18, 2025
The N-heptad repeat (NHR) of the HIV-1 gp41 prehairpin intermediate (PHI) is an attractive potential vaccine target with high sequence conservation across diverse strains. However, despite the potency of NHR-targeting peptides and clinical efficacy o...
Humans Machine Learning Antibodies, Monoclonal Models, Molecular Antibodies, Neutralizing HIV-1 HIV Envelope Protein gp41 HIV Antibodies Neutralization Tests
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Report: Antibacterial activity of a peptide derived from HIV-1 MN strain gp41 envelope glycoprotein against methicillin-resistant Staphylococcus aureus.

Pakistan journal of pharmaceutical sciences Nov 1, 2016
Peptides derived from HIV-1 transmembrane proteins have been extensively studied for antimicrobial activities, and they are known as antimicrobial peptides (AMPs). These AMPs have also been reported to potently combat the drug-resistant microbes. In ...
Humans Anti-Bacterial Agents Microbial Viability Methicillin-Resistant Staphylococcus aureus Dose-Response Relationship, Drug Peptide Fragments Kinetics HIV-1 Erythrocytes Hemolysis HIV Envelope Protein gp41
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