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Methicillin-Resistant Staphylococcus aureus

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[Effect of enzybiotics on the healing of Staphylococcus aureus-infected skin wounds in a pig model].

Klinicka mikrobiologie a infekcni lekarstvi
INTRODUCTION: Staphylococcus aureus is a gram-positive, facultatively anaerobic coccus capable of causing infectious diseases in animals and humans. Especially dangerous are multidrug-resistant forms with poor or even no response to available treatme...

antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota.

Frontiers in cellular and infection microbiology
INTRODUCTION: Antiretroviral therapy has improved life expectancy in HIV-infected patients. However, people living with HIV under antiretroviral therapy are at higher risks of developing chronic complications and acquiring multidrug resistant bacteri...

Effect of palladium(II) complexes on NorA efflux pump inhibition and resensitization of fluoroquinolone-resistant : and approach.

Frontiers in cellular and infection microbiology
leads to diverse infections, and their treatment relies on the use of antibiotics. Nevertheless, the rise of antibiotic resistance poses an escalating challenge and various mechanisms contribute to antibiotic resistance, including modifications to d...

Defining the biomarkers in anti-MRSA fractions of soil Streptomycetes by multivariate analysis.

Antonie van Leeuwenhoek
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most alarming antibiotic-resistant pathogens causing nosocomial and community-acquired infections. Actinomycetes, particularly Streptomycetes, have historically been a major source of n...

Deep learning model for personalized prediction of positive MRSA culture using time-series electronic health records.

Nature communications
Methicillin-resistant Staphylococcus aureus (MRSA) poses significant morbidity and mortality in hospitals. Rapid, accurate risk stratification of MRSA is crucial for optimizing antibiotic therapy. Our study introduced a deep learning model, PyTorch_E...

Detection of hospital super bacteria MRSA from the hands of healthcare professionals using machine learning and hyperspectral imaging.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Healthcare-associated infections resulting from cross-contamination, particularly from the hands of multidisciplinary staff, significantly impact patient mortality in health units. The prolonged nature of classical phenotypic diagnostic methods under...

Machine Learning-Assisted High-Throughput Screening for Anti-MRSA Compounds.

IEEE/ACM transactions on computational biology and bioinformatics
BACKGROUND: Antimicrobial resistance is a major public health threat, and new agents are needed. Computational approaches have been proposed to reduce the cost and time needed for compound screening.

Artificial intelligence-driven quantification of antibiotic-resistant Bacteria in food by color-encoded multiplex hydrogel digital LAMP.

Food chemistry
Antibiotic-resistant bacteria pose considerable risks to global health, particularly through transmission in the food chain. Herein, we developed the artificial intelligence-driven quantification of antibiotic-resistant bacteria in food using a color...

Novel active Trp- and Arg-rich antimicrobial peptides with high solubility and low red blood cell toxicity designed using machine learning tools.

International journal of antimicrobial agents
BACKGROUND: Given the rising number of multidrug-resistant (MDR) bacteria, there is a need to design synthetic antimicrobial peptides (AMPs) that are highly active, non-hemolytic, and highly soluble. Machine learning tools allow the straightforward i...

Machine learning-based prediction model for patients with recurrent Staphylococcus aureus bacteremia.

BMC medical informatics and decision making
BACKGROUND: Staphylococcus aureus bacteremia (SAB) remains a significant contributor to both community-acquired and healthcare-associated bloodstream infections. SAB exhibits a high recurrence rate and mortality rate, leading to numerous clinical tre...