Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Feb 2, 2023
Screening of lymph node metastases in colorectal cancer (CRC) can be a cumbersome task, but it is amenable to artificial intelligence (AI)-assisted diagnostic solution. Here, we propose a deep learning-based workflow for the evaluation of CRC lymph n...
Drug discovery today
Feb 2, 2023
Drug development has become unbearably slow and expensive. A key underlying problem is the clinical prediction challenge: the inability to predict which drug candidates will be safe in the human body and for whom. Recently, a dramatic regulatory chan...
Neural networks : the official journal of the International Neural Network Society
Feb 2, 2023
This paper investigates the approximation properties of deep neural networks with piecewise-polynomial activation functions. We derive the required depth, width, and sparsity of a deep neural network to approximate any Hölder smooth function up to a ...
Drug discovery today
Feb 2, 2023
Over the past decade, the amount of biomedical data available has grown at unprecedented rates. Increased automation technology and larger data volumes have encouraged the use of machine learning (ML) or artificial intelligence (AI) techniques for mi...
Analytical methods : advancing methods and applications
Feb 2, 2023
A nano-ZnS-decorated hierarchically porous carbon (ZSHPC) was mixed with MWCNTs to obtain ZSHPC/MWCNT nanocomposites. Then, ZSHPC/MWCNTs were used to modify a screen-printed electrode, and a portable electrochemical detection system combined with mac...
Environmental science and pollution research international
Feb 1, 2023
Agricultural productivity can be impaired by poor irrigation water quality. Therefore, adequate vulnerability assessment and identification of the most influential water quality parameters for accurate prediction becomes crucial for enhanced water re...
Journal of exposure science & environmental epidemiology
Feb 1, 2023
BACKGROUND: Disparities in adverse COVID-19 health outcomes have been associated with multiple social and environmental stressors. However, research is needed to evaluate the consistency and efficiency of methods for studying these associations at lo...
Current opinion in structural biology
Feb 1, 2023
Drug discovery aims to select proper targets and drug candidates to address unmet clinical needs. The end-to-end drug discovery process includes all stages of drug discovery from target identification to drug candidate selection. Recently, several ar...
Molecular informatics
Feb 1, 2023
In recent years, thanks to advances in computer hardware and dataset availability, data-driven approaches (like machine learning) have become one of the essential parts of the drug design framework to accelerate drug discovery procedures. Constructin...
International journal of neural systems
Feb 1, 2023
In the last years, the number of machine learning algorithms and their parameters has increased significantly. On the one hand, this increases the chances of finding better models. On the other hand, it increases the complexity of the task of trainin...