AIMC Topic: Menthol
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Leveraging machine learning to predict drug permeation: impact of menthol and limonene as enhancers.
Molecular diversity
Dec 16, 2024
The present study aimed to develop robust machine learning (ML) models to predict the skin permeability of poorly water-soluble drugs in the presence of menthol and limonene as penetration enhancers (PEs). The ML models were also applied in virtual s...
Quantitative analysis of menthol in human urine using solid phase microextraction and stable isotope dilution gas chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 13, 2016
To accurately measure menthol levels in human urine, we developed a method using gas chromatography/electron ionization mass spectrometry with menthol-d stable isotope internal standardization. We used solid phase microextraction (SPME) headspace sam...
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