Biological dosimetry is used to estimate individual absorbed radiation dose by quantifying an appropriate biological marker. The most popular gold-standard marker is the appearance of dicentric chromosomes in metaphase. The metaphase finder is a tool...
Chromosome enumeration is an essential but tedious procedure in karyotyping analysis. To automate the enumeration process, we develop a chromosome enumeration framework, DeepACEv2, based on the region based object detection scheme. The framework is d...
Computer methods and programs in biomedicine
33524814
BACKGROUND AND OBJECTIVE: The morphology of the human metaphase II (MII) oocyte is an essential indicator of the embryo's potential for developing into a healthy baby in the Intra-Cytoplasmic Sperm Injection (ICSI) process. In this case, characterist...
Medical & biological engineering & computing
34822119
Chromosomes are bodies that contain human genetic information. Chromosomal disorders can cause structural and functional disorders in individuals. Detecting the metaphase stages of the cells accurately is a crucial step to detect possible defects in ...
Biological dosimetry is used to estimate one's dose by biological phenomena. The most popular and 'gold standard' phenomenon is the appearance of dicentric chromosomes in metaphases. The metaphase finder is a tool for biological dosimetry that finds ...
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
38448018
OBJECTIVE: To train a deep convolutional neural networks (CNN) using a labeled data set to classify the metaphase chromosomes and test its accuracy for chromosomal identification.
Archives of pathology & laboratory medicine
37931220
CONTEXT.—: Conventional karyotype analysis, which provides comprehensive cytogenetic information, plays a significant role in the diagnosis and risk stratification of hematologic neoplasms. The main limitations of this approach include long turnaroun...