AIMC Topic: Cytogenetic Analysis

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Cancer cytogenetics in the era of artificial intelligence: shaping the future of chromosome analysis.

Future oncology (London, England) Aug 12, 2024
Artificial intelligence (AI) has rapidly advanced in the past years, particularly in medicine for improved diagnostics. In clinical cytogenetics, AI is becoming crucial for analyzing chromosomal abnormalities and improving precision. However, existin...
Humans Artificial Intelligence Chromosome Aberrations Cytogenetic Analysis Precision Medicine Neoplasms
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Cytogenetics and genomics in pediatric acute lymphoblastic leukaemia.

Best practice & research. Clinical haematology Aug 17, 2023
The last five decades have witnessed significant improvement in diagnostics, treatment and management of children with acute lymphoblastic leukaemia (ALL). These advancements have become possible through progress in our understanding of the genetic a...
Artificial Intelligence Precursor Cell Lymphoblastic Leukemia-Lymphoma Child Cytogenetic Analysis Genomics Immunotherapy Humans
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Predicting the 1p/19q Codeletion Status of Presumed Low-Grade Glioma with an Externally Validated Machine Learning Algorithm.

Clinical cancer research : an official journal of the American Association for Cancer Research Sep 23, 2019
PURPOSE: Patients with 1p/19q codeleted low-grade glioma (LGG) have longer overall survival and better treatment response than patients with 1p/19q intact tumors. Therefore, it is relevant to know the 1p/19q status. To investigate whether the 1p/19q ...
Chromosome Deletion Cytogenetic Analysis Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 19 Mutation Isocitrate Dehydrogenase Magnetic Resonance Imaging Male Middle Aged Humans Female ROC Curve Machine Learning Brain Neoplasms Algorithms Glioma
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Pharmacokinetics and Safety of Elotuzumab Combined With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma and Various Levels of Renal Impairment: Results of a Phase Ib Study.

Clinical lymphoma, myeloma & leukemia Dec 21, 2015
INTRODUCTION: The present study evaluated the pharmacokinetics and safety of elotuzumab, a humanized IgG1 monoclonal antibody against signaling lymphocyte activation molecule-F7, combined with lenalidomide and dexamethasone, in patients with multiple...
Antineoplastic Combined Chemotherapy Protocols Aged, 80 and over Treatment Outcome Lenalidomide Adult Severity of Illness Index Cytogenetic Analysis Female Kidney Diseases Retreatment Aged Thalidomide Male Dexamethasone Humans Neoplasm Staging Kidney Function Tests Middle Aged Multiple Myeloma Antibodies, Monoclonal, Humanized
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THE PROJECT OF ANOTHER LOW-COST METAPHASE FINDER (SECOND REPORT-APPLICATION OF ARTIFICIAL INTELLIGENCE).

Radiation protection dosimetry Dec 31, 2019
Biological dosimetry is used to estimate individual absorbed radiation dose by quantifying an appropriate biological marker. The most popular gold-standard marker is the appearance of dicentric chromosomes in metaphase. The metaphase finder is a tool...
Artificial Intelligence Software Humans Radiation Dosage Chromosome Aberrations Lymphocytes Microscopy Metaphase Cytogenetic Analysis
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