AIMC Topic: Myosins

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Resilience of hierarchical actuators highlighted by a myosin-to-muscle mock-up.

Bioinspiration & biomimetics
Skeletal muscle is the main actuator of various families of vertebrates (mammals, fish, reptiles). It displays remarkable robustness to micro-damage, that supposedly originates both from its redundant hierarchical structure and its nervous command. A...

Deep learning the structural determinants of protein biochemical properties by comparing structural ensembles with DiffNets.

Nature communications
Understanding the structural determinants of a protein's biochemical properties, such as activity and stability, is a major challenge in biology and medicine. Comparing computer simulations of protein variants with different biochemical properties is...