AIMC Topic: N-Acetylneuraminic Acid

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Rapid total sialic acid monitoring during cell culture process using a machine learning model based soft sensor.

Biotechnology progress Jul 2, 2024
Total sialic acid content (TSA) in biotherapeutic proteins is often a critical quality attribute as it impacts the drug efficacy. Traditional wet chemical assays to quantify TSA in biotherapeutic proteins during cell culture typically takes several h...
Machine Learning Animals CHO Cells Cricetulus Cell Culture Techniques N-Acetylneuraminic Acid
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Examining the Influenza A Virus Sialic Acid Binding Preference Predictions of a Sequence-Based Convolutional Neural Network.

Influenza and other respiratory viruses Dec 1, 2024
BACKGROUND: Though receptor binding specificity is well established as a contributor to host tropism and spillover potential of influenza A viruses, determining receptor binding preference of a specific virus still requires expensive and time-consumi...
Humans Neural Networks, Computer Machine Learning Influenza A virus Protein Binding Amino Acid Sequence Influenza, Human Hemagglutinin Glycoproteins, Influenza Virus Receptors, Virus N-Acetylneuraminic Acid
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