AIMC Topic: Ototoxicity
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Machine learning model identifies genetic predictors of cisplatin-induced ototoxicity in CERS6 and TLR4.
Computers in biology and medicine
Nov 1, 2024
BACKGROUND: Cisplatin-induced ototoxicity remains a significant concern in pediatric cancer treatment due to its permanent impact on quality of life. Previously, genetic association analyses have been performed to detect genetic variants associated w...
In silico prediction of drug-induced ototoxicity using machine learning and deep learning methods.
Chemical biology & drug design
Jun 7, 2021
Drug-induced ototoxicity has become a serious global problem, because of leading to deafness in hundreds of thousands of people every year. It always results from exposure to drugs or environmental chemicals that cause the impairment and degeneration...
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