AIMC Topic: Phage Therapy

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Optimizing phage therapy with artificial intelligence: a perspective.

Frontiers in cellular and infection microbiology
Phage therapy is emerging as a promising strategy against the growing threat of antimicrobial resistance, yet phage and bacteria are incredibly diverse and idiosyncratic in their interactions with one another. Clinical applications of phage therapy o...

PhageLeads: Rapid Assessment of Phage Therapeutic Suitability Using an Ensemble Machine Learning Approach.

Viruses
The characterization of therapeutic phage genomes plays a crucial role in the success rate of phage therapies. There are three checkpoints that need to be examined for the selection of phage candidates, namely, the presence of temperate markers, anti...

A solution to the postantibiotic era: phages as precision medicine.

Current opinion in microbiology
Antibiotic-resistant bacterial infections pose a significant global health challenge. Phage therapy provides a promising alternative to antibiotics that enables the specific targeting of pathogenic bacteria while preserving the healthy microbiome. Re...