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Porphobilinogen Synthase

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Detecting rare diseases in electronic health records using machine learning and knowledge engineering: Case study of acute hepatic porphyria.

PloS one
BACKGROUND: With the growing adoption of the electronic health record (EHR) worldwide over the last decade, new opportunities exist for leveraging EHR data for detection of rare diseases. Rare diseases are often not diagnosed or delayed in diagnosis ...

Reducing diagnostic delays in acute hepatic porphyria using health records data and machine learning.

Journal of the American Medical Informatics Association : JAMIA
BACKGROUND: Acute hepatic porphyria (AHP) is a group of rare but treatable conditions associated with diagnostic delays of 15 years on average. The advent of electronic health records (EHR) data and machine learning (ML) may improve the timely recogn...