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Receptors, Thyrotropin

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Computational model of the full-length TSH receptor.

eLife
(GPCR)The receptor for TSH receptor (TSHR), a G protein coupled receptor (GPCR), is of particular interest as the primary antigen in autoimmune hyperthyroidism (Graves' disease) caused by stimulating TSHR antibodies. To date, only one domain of the e...

Potential impact of organophosphate esters on thyroid eye disease based on machine learning and molecular docking.

The Science of the total environment
Organophosphate esters (OPEs) are widely used as flame retardants and plasticizers in daily commodities and building materials. Some OPEs, acting as agonists of the thyroid-stimulating hormone receptor (TSHR), may contribute to the development of thy...