AIMC Topic: Receptors, Thyrotropin
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The evolving therapeutic landscape of Graves' disease in adults: present and future.
European thyroid journal
Jul 22, 2025
The therapeutic landscape of Graves' hyperthyroidism has been rapidly evolving in the past few years. There has been a shift worldwide toward antithyroid drugs as the preferred first-line therapy with significant interest in thyroid function preserva...
Potential impact of organophosphate esters on thyroid eye disease based on machine learning and molecular docking.
The Science of the total environment
Dec 3, 2024
Organophosphate esters (OPEs) are widely used as flame retardants and plasticizers in daily commodities and building materials. Some OPEs, acting as agonists of the thyroid-stimulating hormone receptor (TSHR), may contribute to the development of thy...
Computational model of the full-length TSH receptor.
eLife
Oct 28, 2022
(GPCR)The receptor for TSH receptor (TSHR), a G protein coupled receptor (GPCR), is of particular interest as the primary antigen in autoimmune hyperthyroidism (Graves' disease) caused by stimulating TSHR antibodies. To date, only one domain of the e...
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